[proxy] pubmed.ncbi.nlm.nih.gov — ← back | site home | direct (HTTPS) ↗ | proxy home | ◑ dark◐ light

Circadian topology of metabolism - PubMed

Joseph Bass  1

Review

. 2012 Nov 15;491(7424):348-56.

doi: 10.1038/nature11704.

Affiliations

Review

Circadian topology of metabolism

Joseph Bass. Nature. .

Abstract

Biological clocks are genetically encoded oscillators that allow organisms to anticipate changes in the light-dark environment that are tied to the rotation of Earth. Clocks enhance fitness and growth in prokaryotes, and they are expressed throughout the central nervous system and peripheral tissues of multicelled organisms in which they influence sleep, arousal, feeding and metabolism. Biological clocks capture the imagination because of their tie to geophysical time, and tools are now in hand to analyse their function in health and disease at the cellular and molecular level.

PubMed Disclaimer

References

    1. Genes Dev. 2008 Jun 1;22(11):1513-21 - PubMed
    1. PLoS Biol. 2011 Feb;9(2):e1000595 - PubMed
    1. Genes Dev. 2010 Feb 15;24(4):345-57 - PubMed
    1. Science. 2009 Oct 16;326(5951):437-40 - PubMed
    1. Mol Endocrinol. 2005 Jun;19(6):1452-9 - PubMed

LinkOut - more resources