Abstract
The ability of fibroblasts to perform unscheduled DNA synthesis (a measure of excision-repair) after UV irradiation was measured radioautographically for seven species at several times after several UV fluences. Both the initial rate and the maximum incorporation of [3H]dThd increased with the life-span of the species (shrew, mouse, rat, hamster, cow, elephant, man). Unscheduled DNA synthesis was approximately proportional to the logarithm of life-span.
- Publication:
-
Proceedings of the National Academy of Science
- Pub Date:
- June 1974
- DOI:
- Bibcode:
- 1974PNAS...71.2169H