These are the spammers you definitely do NOT want on your network.
Many of these spam operations pretend to operate 'offshore' using servers in Asia and South America. Those who don't pretend to be 'offshore' pretend to be small ISPs themselves, claiming to their providers the spam is being sent not by them but by non-existent 'customers'. When caught, almost all use the age old tactic of lying to each ISP long enough to buy a few weeks more of spamming and when terminated simply move on to the next ISP already set up and waiting.
ROKSO is a "3 Strikes" register. To be placed on the ROKSO list a spammer must first be terminated by a minimum of 3 ISPs for AUP violations. Once listed in ROKSO, IP addresses under the control of ROKSO-listed spammers are automatically and preemptively listed in the Spamhaus Block List (SBL).
Spamhaus also publishes a weekly TOP 10 "Worst ROKSO Spammers" chart.