General Information
Symbol
Dmel\CycA
Species
D. melanogaster
Name
Cyclin A
Annotation Symbol
CG5940
Feature Type
FlyBase ID
FBgn0000404
Gene Model Status
Stock Availability
Gene Summary
Cyclin A (CycA) encodes a protein that binds to the product of Cdk1, thereby promoting Cdk1's protein kinase activity. The CycA-Cdk1 complex controls important aspects of progression through the cell cycle, including entry into mitosis. During the G2 phase, this complex is important for prevention of premature DNA re-replication. During mitosis and G1, the product of CycA is rapidly degraded (involving APC/C and the proteasome), resulting in inactivation of Cdk1 protein kinase activity. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)
Also Known As
Cyc A, dCycA, rsg11, DmcycA
Key Links
Genomic Location
Cytogenetic map
Sequence location
Recombination map
3-37
RefSeq locus
Sequence
Genomic Maps
Other Genome Views
Function
Gene Ontology (GO) Annotations (20 terms)
Molecular Function (2 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
inferred from direct assay
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
non-traceable author statement
Biological Process (9 terms)
Terms Based on Experimental Evidence (9 terms)
CV Term
Evidence
References
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from expression pattern
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
Cellular Component (9 terms)
Terms Based on Experimental Evidence (7 terms)
CV Term
Evidence
References
inferred from direct assay
inferred from direct assay
inferred from direct assay
inferred from direct assay
inferred from direct assay
inferred from direct assay
inferred from direct assay
inferred from direct assay
inferred from direct assay
Terms Based on Predictions or Assertions (4 terms)
CV Term
Evidence
References
Gene Group (FlyBase)
Belongs to the cyclin family. Cyclin AB subfamily. (P14785)
Summaries
Gene Snapshot
Cyclin A (CycA) encodes a protein that binds to the product of Cdk1, thereby promoting Cdk1's protein kinase activity. The CycA-Cdk1 complex controls important aspects of progression through the cell cycle, including entry into mitosis. During the G2 phase, this complex is important for prevention of premature DNA re-replication. During mitosis and G1, the product of CycA is rapidly degraded (involving APC/C and the proteasome), resulting in inactivation of Cdk1 protein kinase activity. [Date last reviewed: 2019-03-07]
Protein Function (UniProtKB)
Essential for the control of the cell cycle at the G2/M (mitosis) transition. Interacts with the Cdk1 and Cdk2 protein kinases to form MPF. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis.
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
CycA: Cyclin A
Encodes cyclin, a molecule involved in the cell cycle; the pattern of transcription reflects this. Maternal message uniformly distributed in newly laid egg, but becomes more concentrated in the cortex prior to peripheral nuclear migration. At the time of cellularization of the blastoderm, zygotic message is produced. Cyclin A accumulates in the interphase cytoplasm of cellularized embryos, but relocates to the nuclear region early in prophase and is completely degraded during metaphase. A functional cyclin A gene is required for continued cell division after exhaustion of maternally provided cyclin A. Message confined to dividing tissues in brain and imaginal disks in larvae.
Summary (Interactive Fly)
a a G2-M phase cyclin - cell cycle regulator - dimerization partner of Cdk1/Cdc2 kinase - during the G2 phase the CycA-Cdk1 prevents premature DNA re-replication - during mitosis and G1, CycA is rapidly degraded resulting in inactivation of Cdk1 protein kinase activity
Gene Model and Products
Expression Data
Testis-specificity index
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
No Assay Recorded
Stage
Tissue/Position (including subcellular localization)
Reference
distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
western blot
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
The cyclins are normally found in the cytoplasm of interphase cells and become nuclear in prophase cells. CycA protein is abruptly degraded and is not detectable in metaphase or anaphase cells. Cells of embryos heat shocked in G2 phase of cycle 14 show very high levels of the cyclins and cyclin degradation is delayed: heat shock causes a disruption in cell cycle progression.
The highest CycA protein concentration is found in the cytoplasm at interphase. CycA protein associates with chromatin during mitosis. It is not completely degraded at the metaphase-anaphase transition in syncytial embryos.
CycA protein is initially distributed uniformly throughout the syncytial embryo. It becomes concentrated in the cortex in a 30-40 micron deep layer as nuclei migrate to the surface.
Marker for
Subcellular Localization
CV Term
Evidence
References
inferred from direct assay
inferred from direct assay
inferred from direct assay
inferred from direct assay
inferred from direct assay
inferred from direct assay
inferred from direct assay
inferred from direct assay
inferred from direct assay
Expression Deduced from Reporters
Stage
Tissue/Position (including subcellular localization)
Reference
Stage
Tissue/Position (including subcellular localization)
Reference
Stage
Tissue/Position (including subcellular localization)
Reference
Stage
Tissue/Position (including subcellular localization)
Reference
Stage
Tissue/Position (including subcellular localization)
Reference
Stage
Tissue/Position (including subcellular localization)
Reference
Stage
Tissue/Position (including subcellular localization)
Reference
Stage
Tissue/Position (including subcellular localization)
Reference
Stage
Tissue/Position (including subcellular localization)
Reference
Stage
Tissue/Position (including subcellular localization)
Reference
Stage
Tissue/Position (including subcellular localization)
Reference
Stage
Tissue/Position (including subcellular localization)
Reference
High-Throughput Expression Data
Associated Tools
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
Reference
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
Images
FlyExpress - Embryonic expression images (BDGP data)
Stages(s) 4-6
Stages(s) 7-8
Stages(s) 9-10
Stages(s) 11-12
Stages(s) 13-16
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 47 )
For All Classical and Insertion Alleles Show
Other relevant insertions
Transgenic Constructs ( 49 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of CycA
Transgenic constructs containing regulatory region of CycA
Aberrations (Deficiencies and Duplications) ( 16 )
Inferred from experimentation ( 16 )
Gene disrupted in
Gene not disrupted in
Inferred from location ( 7 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
anaphase & condensed nuclear chromosome
metaphase & condensed nuclear chromosome
Orthologs
Downloads
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Alignment
Complementation?
Transgene?
12 of 14
Yes
Yes
11 of 14
No
Yes
7 of 14
No
No
6 of 14
No
No
4 of 14
No
No
4 of 14
No
No
3 of 14
No
No
3 of 14
No
Yes
3 of 14
No
No
3 of 14
No
No
3 of 14
No
Yes
3 of 14
No
No
3 of 14
No
No
2 of 14
No
No
2 of 14
No
No
2 of 14
No
No
2 of 14
No
No
2 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Alignment
Complementation?
Transgene?
12 of 14
Yes
Yes
11 of 14
No
Yes
6 of 14
No
No
4 of 14
No
No
4 of 14
No
No
3 of 14
No
No
3 of 14
No
Yes
3 of 14
No
No
3 of 14
No
No
3 of 14
No
No
3 of 14
No
No
2 of 14
No
No
2 of 14
No
No
2 of 14
No
No
2 of 14
No
No
1 of 14
No
Yes
1 of 14
No
No
1 of 14
No
Yes
11 of 14
Yes
Yes
11 of 14
Yes
Yes
7 of 14
No
No
6 of 14
No
No
4 of 14
No
No
4 of 14
No
No
3 of 14
No
No
3 of 14
No
Yes
3 of 14
No
No
3 of 14
No
No
3 of 14
No
No
3 of 14
No
No
2 of 14
No
No
2 of 14
No
No
2 of 14
No
No
2 of 14
No
No
1 of 14
No
No
7 of 13
Yes
Yes
6 of 13
No
No
6 of 13
No
Yes
5 of 13
No
Yes
4 of 13
No
No
4 of 13
No
No
4 of 13
No
No
3 of 13
No
No
3 of 13
No
No
2 of 13
No
No
2 of 13
No
No
2 of 13
No
Yes
2 of 13
No
No
1 of 13
No
Yes
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
Yes
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
Yes
1 of 13
No
No
1 of 13
No
Yes
1 of 13
No
No
1 of 13
No
Yes
1 of 13
No
No
1 of 13
No
No
1 of 13
No
Yes
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
Yes
1 of 13
No
Yes
1 of 13
No
No
1 of 13
No
No
12 of 14
Yes
Yes
11 of 14
No
Yes
7 of 14
No
No
6 of 14
No
No
4 of 14
No
No
3 of 14
No
No
3 of 14
No
No
3 of 14
No
No
3 of 14
No
Yes
3 of 14
No
No
2 of 14
No
No
2 of 14
No
No
2 of 14
No
No
2 of 14
No
Yes
2 of 14
No
No
2 of 14
No
No
2 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
9 of 14
Yes
Yes
7 of 14
No
No
7 of 14
No
No
7 of 14
No
No
3 of 14
No
Yes
3 of 14
No
No
3 of 14
No
Yes
3 of 14
No
Yes
2 of 14
No
No
2 of 14
No
Yes
2 of 14
No
Yes
2 of 14
No
Yes
2 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
Yes
12 of 12
Yes
Yes
5 of 12
No
No
5 of 12
No
No
4 of 12
No
No
3 of 12
No
No
2 of 12
No
No
2 of 12
No
No
1 of 12
No
No
1 of 12
No
No
1 of 12
No
No
1 of 12
No
No
1 of 12
No
No
1 of 12
No
No
1 of 12
No
No
1 of 12
No
No
11 of 13
Yes
Yes
11 of 13
Yes
Yes
10 of 13
No
Yes
10 of 13
No
Yes
10 of 13
No
Yes
10 of 13
No
Yes
10 of 13
No
Yes
10 of 13
No
Yes
10 of 13
No
Yes
10 of 13
No
Yes
7 of 13
No
No
7 of 13
No
No
7 of 13
No
No
7 of 13
No
No
7 of 13
No
No
7 of 13
No
No
6 of 13
No
Yes
6 of 13
No
No
6 of 13
No
No
6 of 13
No
No
6 of 13
No
No
3 of 13
No
Yes
2 of 13
No
No
2 of 13
No
No
2 of 13
No
No
2 of 13
No
No
2 of 13
No
No
2 of 13
No
No
2 of 13
No
No
2 of 13
No
No
2 of 13
No
No
2 of 13
No
No
1 of 13
No
Yes
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
Yes
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
7 of 13
Yes
No
7 of 13
Yes
No
7 of 13
Yes
Yes
6 of 13
No
No
6 of 13
No
No
6 of 13
No
No
4 of 13
No
Yes
4 of 13
No
Yes
3 of 13
No
Yes
1 of 13
No
No
1 of 13
No
No
7 of 12
Yes
No
7 of 12
Yes
No
6 of 12
No
No
4 of 12
No
Yes
3 of 12
No
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:CycA. Refer to their site for version information.
Paralogs
Downloads
Paralogs (via DIOPT v9.1)
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Allele
Disease
Evidence
References
Potential Models Based on Orthology ( 0 )
Human Ortholog
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 3 )
Allele
Disease
Interaction
References
Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
Functional Complementation Data
Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
Interactions
Summary of Physical Interactions
Interaction Browsers
Please see the Physical Interaction reports below for full details
protein-protein
Physical Interaction
Assay
References
(Darnat et al., 2022, Ayeni et al., 2014, Guruharsha et al., 2011, Gawlinski et al., 2007, Avedisov et al., 2000, Lane et al., 1996, Sauer et al., 1996, Knoblich et al., 1994)
RNA-protein
Physical Interaction
Assay
References
Summary of Genetic Interactions
Interaction Browsers
Please look at the allele data for full details of the genetic interactions
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
suppressible
enhanceable
suppressible
enhanceable
suppressible
suppressible
suppressible
enhanceable
enhanceable
suppressible
enhanceable
suppressible
suppressible
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
enhanceable
suppressible
suppressible
suppressible
suppressible
suppressible
enhanceable
suppressible
suppressible
suppressible
suppressible
enhanceable
suppressible
suppressible
suppressible
suppressible
enhanceable
enhanceable
suppressible
suppressible
enhanceable
suppressible
enhanceable
suppressible
suppressible
enhanceable
suppressible
enhanceable
suppressible
suppressible
External Data
Subunit Structure (UniProtKB)
Component of the Frs-CycA-Cdk1 complex composed of CycA, Cdk1 and Z600 (PubMed:17431409). Interacts (via C-terminus) with Z600 (PubMed:17431409). Interacts with otu and (via C-terminus) with bam; the interaction stabilizes CycA by negatively regulating its ubiquitination (PubMed:28484036).
Linkouts
Pathways
Signaling Pathways (FlyBase)
Metabolic Pathways
External Data
Class of Gene
Genomic Location and Detailed Mapping Data
Chromosome (arm)
3L
Recombination map
3-37
Cytogenetic map
Sequence location
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
68E1-68E1
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
68E1-68E2
(determined by in situ hybridisation)
68E-68E
(determined by in situ hybridisation)
68E1-68E2
68E1--3
68D-68E
(determined by in situ hybridisation)
Experimentally Determined Recombination Data
Location
3-37
3-30.3
3-37.6--39
Left of (cM)
Right of (cM)
Notes
Stocks and Reagents
Stocks (31)
91660
83154
6633
85308
91661
F001387
F001176
123684
5940R-1
5940R-4
v103595
v32421
Genomic Clones (22)
cDNA Clones (341)
RNAi and Array Information
Linkouts
Antibody Information
Cell Line Information
Publicly Available Cell Lines
Other Stable Cell Lines
Relationship to Other Genes
Source for database merge of
Source for merge of: CycA anon-WO0140519.128
Additional comments
Source for merge of CycA anon-WO0140519.128 was sequence comparison ( date:051113 ).
Nomenclature History
Source for database identify of
Source for identity of: CycA CG5940
Nomenclature comments
Etymology
Synonyms and Secondary IDs (35)
Reported As
Symbol Synonym
0033/02
0040/24
0046/23
0104/07
0245/34
0521/06
0545/13
1329/16
1449/05
CG5940
(Ibaraki et al., 2021, Neuert et al., 2017, Hosono et al., 2015, Zeng et al., 2015, Fukuoh et al., 2014, Cui et al., 2013, Schertel et al., 2013, Ni et al., 2011.7.19, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Pan and Zhang, 2009, Perkins et al., 2009, Haussmann et al., 2008, Ni et al., 2008, Wheeler et al., 2004)
CLD3
CYCA
CYCLIN A
Cyc A
CycA
(Arnce et al., 2025, Kagemann et al., 2025, Bourouh et al., 2024, Goins et al., 2024, Isaacson et al., 2024, Matthew et al., 2024, Trujillo et al., 2024, Vasavan et al., 2024, Vesala et al., 2024, Avellino et al., 2023, Neophytou et al., 2023, Olivares et al., 2023, Riemondy et al., 2023, Zhang et al., 2023, Almeida Machado Costa et al., 2022, Darnat et al., 2022, Diegmiller et al., 2022, Eickelberg et al., 2022, Nadimpalli et al., 2022, Bailey et al., 2021, Ferguson et al., 2021, Ibaraki et al., 2021, Parkhitko et al., 2021, Zhang et al., 2021, Cho et al., 2020, Hur et al., 2020, Kordyukova et al., 2020, Mishra et al., 2020, Shi et al., 2020, Vaccaro et al., 2020, Willms et al., 2020, Zhao et al., 2020, Archambault, 2019.12.8, Blake-Hedges and Megraw, 2019, Greenblatt et al., 2019, Harding and White, 2019, Kondo and Hayashi, 2019, Liao et al., 2019, Parker et al., 2019, Rivera et al., 2019, Rotelli et al., 2019, Eusebio et al., 2018, Flora et al., 2018, García Del Arco et al., 2018, Gene Disruption Project members, 2018-, Hakes et al., 2018, Hao et al., 2018, Otsuki and Brand, 2018, Swevers et al., 2018, Wu et al., 2018, Hara et al., 2017, Heseding et al., 2017, Housden et al., 2017, Ji et al., 2017, Liu et al., 2017, Martins et al., 2017, Neto et al., 2017, Neuert et al., 2017, Recasens-Alvarez et al., 2017, Siddall and Hime, 2017, Tomita et al., 2017, Transgenic RNAi Project members, 2017-, Weber and Mlodzik, 2017, Bourouh et al., 2016, Chandra et al., 2016, Gomez et al., 2016, Meghini et al., 2016, Qi and Calvi, 2016, Ricolo et al., 2016, Varadarajan et al., 2016, Afonso et al., 2015, Afonso et al., 2015, Bergman et al., 2015, Di Cara et al., 2015, Doggett et al., 2015, Gene Disruption Project members, 2015-, Matsuda et al., 2015, Wang and Baker, 2015, Ashwal-Fluss et al., 2014, Butí et al., 2014, Eliazer et al., 2014, Frost et al., 2014, Günesdogan et al., 2014, Hassel et al., 2014, Parsons et al., 2014, Singh et al., 2014, Bandura et al., 2013, Bonke et al., 2013, Chang et al., 2013, Kondo and Hayashi, 2013, Lehner, 2013.1.1, Lu et al., 2013, Mishra et al., 2013, Neumüller et al., 2013, Noatynska et al., 2013, Organista and De Celis, 2013, Saunders et al., 2013, Schertel et al., 2013, Yin et al., 2013, Zhou and Luo, 2013, Farrell et al., 2012, Ito et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Ruggiero et al., 2012, Sallé et al., 2012, Tokusumi et al., 2012, van der Harst et al., 2012, Xu et al., 2012, Xu et al., 2012, Yuan et al., 2012, Bangi et al., 2011, Chen et al., 2011, Gilbert et al., 2011, Lindquist et al., 2011, Noyes et al., 2011, Poulton et al., 2011, Richter et al., 2011, Beam and Moberg, 2010, Beck et al., 2010, Biehs et al., 2010, Fox et al., 2010, Li et al., 2010, Monk et al., 2010, Swaminathan et al., 2010, Tastan et al., 2010, zur Lage and Jarman, 2010, Althoff et al., 2009, McCleland et al., 2009, Peng and Karpen, 2009, Shyu et al., 2009, Southall and Brand, 2009, Bakal et al., 2008, Benoit et al., 2008, Bowman et al., 2008, Caussinus et al., 2008, Christensen et al., 2008.12.28, Christensen et al., 2008.12.28, Lee et al., 2008, O'Farrell and Kylsten, 2008, Sato et al., 2008, Shimizu et al., 2008, Ambrus et al., 2007, Beltran et al., 2007, Escudero and Freeman, 2007, Franklin-Dumont et al., 2007, Gawlinski et al., 2007, Gawlinski et al., 2007, Griffiths et al., 2007, Großhans et al., 2007, Johnson et al., 2007, Kankel et al., 2007, Kugler and Nagel, 2007, LaRocque et al., 2007, LaRocque et al., 2007, Lecuyer et al., 2007, Link et al., 2007, Magalhaes et al., 2007, Minakhina et al., 2007, Pfleger et al., 2007, Ramachandran et al., 2007, Sandmann et al., 2007, Sun and Deng, 2007, Swan and Schupbach, 2007, Tanaka-Matakatsu et al., 2007, Tanaka-Matakatsu et al., 2007, Friedman and Perrimon, 2006, Jones et al., 2006, Jordan et al., 2006, Khurana et al., 2006, Morris et al., 2006, Mukherjee et al., 2006, Sugimura and Lilly, 2006, Vrailas and Moses, 2006, Zielke et al., 2006, Baonza and Freeman, 2005, Greene et al., 2005, Stanyon et al., 2004, Heriche et al., 2003, Leismann and Lehner, 2003, Huang and Raff, 2002)
Cyclin A
CyclinA
DmcycA
S(rux)3B
anon-WO0140519.128
cycA
(Kim et al., 2021, Keane et al., 2020, Liaw and Chiang, 2019, Ray et al., 2019, Kim et al., 2018, Lefebvre and Lécuyer, 2018, Ji et al., 2017, Jahanshahi et al., 2016, Kotov et al., 2016, Barckmann et al., 2015, Flores et al., 2015, Lu and Fuller, 2015, Kuang et al., 2014, Buster et al., 2013, Sun and Spradling, 2013, Ruggiero et al., 2012, Sun and Spradling, 2012, Zhai et al., 2012, Vincent et al., 2011, Silies and Klämbt, 2010, Chen et al., 2009, Kwon et al., 2009, McClure and Schubiger, 2008, Scaria et al., 2008, Orian et al., 2007, Szabó et al., 2007, McEllin et al., 2006, Chen et al., 2005, Morris et al., 2005, Ayyar et al., 2003, Heriche et al., 2003, Park et al., 2003, Grosskortenhaus and Sprenger, 2002, Ji et al., 2002, Nakato et al., 2002, Akiyama-Oda et al., 2000, Beitel and Krasnow, 2000, Li and Vaessin, 2000, Myster and Duronio, 2000, Greaves et al., 1999, Lear et al., 1999, Truong et al., 1999, Wai et al., 1999, Dong et al., 1997, Salzberg et al., 1997, Sweeney et al., 1997, Hassan and Vassin, 1996, Salzberg and Bellen, 1996, Sauer et al., 1995, Edgar et al., 1994, Salzberg et al., 1994, Thomas et al., 1994, Foe et al., 1993)
cyclin A
dCycA
hari
l(3)03946
l(3)183
l(3)68Ea
l(3)j3C8
l(3)neo114
l(3)rsg11
rsg11
Name Synonyms
Cyclin A
(Bhattacharya et al., 2024, Rangone et al., 2024, Bakshi et al., 2023, Tzortzopoulos et al., 2019, Ly et al., 2018, Tomita et al., 2017, Cruz-Becerra et al., 2016, Kotov et al., 2016, Dequéant et al., 2015, Ayeni et al., 2014, Günesdogan et al., 2014, Hassel et al., 2014, Khadilkar et al., 2014, Kuang et al., 2014, Bandura et al., 2013, Lu et al., 2013, Potdar and Sheeba, 2013, Whitfield et al., 2013, Zhou and Luo, 2013, Kanakousaki and Gibson, 2012, Kelsom and Lu, 2012, Ruggiero et al., 2012, Gilbert et al., 2011, O'Keefe et al., 2011, Poulton et al., 2011, Beam and Moberg, 2010, Fox et al., 2010, Li et al., 2010, Monk et al., 2010, Papoulas et al., 2010, Swaminathan et al., 2010, zur Lage and Jarman, 2010, Althoff et al., 2009, Merkle et al., 2009, Morris et al., 2009, Benoit et al., 2008, Caussinus et al., 2008, Narbonne-Reveau et al., 2008, Scaria et al., 2008, Sukhanova and Du, 2008, Zhu et al., 2008, Zielke et al., 2008, Escudero and Freeman, 2007, Franklin-Dumont et al., 2007, Franklin-Dumont et al., 2007, Garcia et al., 2007, Kankel et al., 2007, Kaplow et al., 2007, Kugler and Nagel, 2007, Pesin and Orr-Weaver, 2007, Pfleger et al., 2007, Ramachandran et al., 2007, Rickmyre et al., 2007, Sun and Deng, 2007, Swan and Schupbach, 2007, Takada et al., 2007, Khurana et al., 2006, Pines, 2006, Reber et al., 2006, Silva et al., 2006, Vrailas and Moses, 2006, Vrailas et al., 2006, Zielke et al., 2006, Baonza and Freeman, 2005, Mandal et al., 2005, Thomas, 2005, Loop et al., 2004, Wheeler et al., 2004, Furukawa et al., 2003)
CyclinA
Suppressor of rux 3B
cyclin A
(Shafer, 2025, Funato, 2020, Otsuki and Brand, 2020, Liao et al., 2019, Liu and Grosshans, 2017, Khadilkar et al., 2014, Temme et al., 2014, Cui et al., 2013, Noatynska et al., 2013, Robertson and Keene, 2013, Zhan et al., 2013, Matunis et al., 2012, Andersen et al., 2010, Horb and Horb, 2010, Oliveira et al., 2010, Anderson et al., 2009, Baldinger and Gossen, 2009, Benoit et al., 2009, Chen et al., 2009, Shyu et al., 2009, Vardy et al., 2009, Chia et al., 2008, Erhardt et al., 2008, González et al., 2008, Kotadia et al., 2008, Lee et al., 2008, McCleland and O'Farrell, 2008, McClure and Schubiger, 2008, Shimizu et al., 2008, Brunk et al., 2007, Huang et al., 2007, Huang et al., 2007, Kaplow et al., 2007, Link et al., 2007, Pal et al., 2007, Ringrose and Paro, 2007, Sakaguchi and Steward, 2007, Tadros et al., 2007, Tanaka-Matakatsu et al., 2007, Maurange et al., 2006, Muller and Kassis, 2006, Wodarz and Gonzalez, 2006, Baonza and Freeman, 2005, Chen et al., 2005, Findlay et al., 2005, Frolov et al., 2005, Hyun et al., 2005, Lopes et al., 2005, Wheeler et al., 2004, Douglas and Haddad, 2003, Lee and Orr-Weaver, 2003, Purdy and Su, 2003, Fung et al., 2002, Huang and Raff, 2002, Mihaylov et al., 2002, Nagao and Yanagida, 2002, Nieduszynski et al., 2002, Deng and Lin, 2001, Mahowald, 2001, O'Farrell, 2001, Jaklevic et al., 2000, Lilly et al., 2000, Harper and Elledge, 1998, de Cuevas et al., 1997, Su and O'Farrell, 1997, Sigrist et al., 1995)
cyclin-A
cyclinA
rose-gespleten region interval 11
Secondary FlyBase IDs
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External Crossreferences and Linkouts ( 78 )
Sequence Crossreferences
NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
Other crossreferences
Linkouts
References (668)